1. What will be the sequence of mRNA produced by the following stretch of DNA?
3'ATGCATGCATGCATG 5' TEMPLATE STRAND 5' TACGTACGTACGTAC 3' CODING STRAND

A 3' AUGCAUGCAUGCAUG 3'
B 3' AUGCAUGCAUGCAUG 5'
C 5' UACGUACGUACGUAC 3'
D 3' UACGUACGUACGUAC 5'
Answer :   5' UACGUACGUACGUAC 3'
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2. One function of the telomeres in a chromosome is to

A indentify the correct number of the homologous pair of chromosomes
B help two chromatids to move towards poles
C "seal" the ends of chromosomes
D start RNA synthesis
Answer :   "seal" the ends of chromosomes
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3. Which one of the following is not applicable to RNA?

A 5' phosphoryl and 3' hydroxyl ends
B Heterocyclic nitrogenous bases
C Chargaff's rule
D Complementary base pairing
Answer :   Chargaff's rule
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4. A sequential expression of a set of human genes

A messenger RNA
B DNA sequence
C ribosome
D transfer RNA
Answer :   DNA sequence
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5. Given below is a sample of a portion of DNA strand. What is so special shown in it?
5' -- GAATTC -- 3'
3' -- CTTAAG -- 5'

A Replication completed
B Deletion mutation
C Start codon at the 5' end
D Palindromic sequence of base pairs
Answer :   Palindromic sequence of base pairs
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6. In which direction m-RNA is synthesised on DNA template ?

A 5' → 3'
B 3' → 5'
C Both (A) and (B)
D Any
Answer :   5' → 3'
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7. In the process of transcription in Eukaryotes, the RNA polymerase I transcribes -

A Precursor of mRNA, hnRNA
B mRNA with additional processing, capping and tailing
C tRNA, 5 srRNA and snRNAs
D rRNAs - 28 S, 18 S and 5.8 S
Answer :   rRNAs - 28 S, 18 S and 5.8 S
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8. In the genetic code dictionary, how many codons are used to code for all the 20 essential amino acids ?

A 60
B 20
C 64
D 61
Answer :   61
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9. The diagram shows an important concept in the genetic implication of DNA. Fill in the blanks $$A$$ to $$C.$$
Molecular Basis of Inheritance mcq question image

A $$A$$-translation $$B$$- transciption $$C$$-Erwin Chargaff
B $$A$$-transcription $$B$$- translation $$C$$-Francis Crick
C $$A$$-translation $$B$$- extension $$C$$-Rosalind Franklin
D $$A$$-transcription $$B$$- replication $$C$$-James Watson
Answer :   $$A$$-transcription $$B$$- translation $$C$$-Francis Crick
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10. During DNA replication, Okazaki fragments are used to elongate:

A The lagging strand towards replication fork
B The leading strand away from replication fork
C The lagging strand away from the replication fork
D The leading strand towards replication fork
Answer :   The lagging strand away from the replication fork
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