11. Which of the following is a restriction endonuclease?

A Hind II
B Protease
C DNase I
D RNase
Answer :   Hind II
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12. DNA precipitation out of a mixture of biomolecules can be achieved by treatment with:

A Isopropanol
B Chilled ethanol
C Methanol at room temperature
D Chilled chloroform
Answer :   Chilled ethanol
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13. Commonly used vectors for human genome sequencing are:

A T-DNA
B BAC and YAC
C Expression Vectors
D kT/A Cloning Vectors
Answer :   BAC and YAC
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14. Which vector can clone only a small fragment of DNA?

A Bacterial artificial chromosome
B Yeast artificial chromosome
C Plasmid
D Cosmid
Answer :   Plasmid
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15. The taq polymerase enzyme is obtained from

A Thermus aquaticus
B Thiobacillus ferroxidans
C Bacillus subtilis
D Pseudomonas putida
Answer :   Thermus aquaticus
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16. Following statements describe the characteristics of the enzyme Restriction Endonuclease. Identify the incorrect statement.

A The enzyme cuts DNA molecule at identified position within the DNA
B The enzyme binds DNA at specific sites and cuts only one of the two strands
C The enzyme cuts the sugar-phosphate backbone at specific sites on each strand
D The enzyme recognizes a specific palindromic nucleotide sequence in the DNA
Answer :   The enzyme binds DNA at specific sites and cuts only one of the two strands
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17. Identify the wrong statement with regard to Restriction Enzymes.

A They cut the strand of DNA at palindromic sites
B They are useful in genetic engineering
C Sticky ends can be joined by using DNA ligases
D Each restriction enzyme functions by inspecting the length of a DNA sequence
Answer :   Sticky ends can be joined by using DNA ligases
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18. The colonies of recombinant bacteria appear white in contrast to blue colonies of non- recombinant bateria because of:

A Insertional inactivate of alphaga- lactosidase in non-recombinant bacteria
B Insertional inactivation of alpha- galactosidase in recombinant bacteria
C Inactivation of glycosidase enzyme in recombinant bacteria
D Non-recombinant bacteria containing beta-galactosidase
Answer :   Non-recombinant bacteria containing beta-galactosidase
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19. There is a restriction endonuclease called EcoRI. What does "co" part in it stand for?

A colon
B coelom
C coenzyme
D coli
Answer :   coli
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20. The plasmids pesent in the bacterial cells are

A circular double helical DNA molecules
B circular double helical RNA molecules
C linear double helical DNA molecules
D linear double helical RNA molecules
Answer :   circular double helical DNA molecules
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